With the advent of audio and video recording on modern digital cameras ( as opposed to the old cylnder gramophones we used to use with the dageurreotypes ) a whole new species of gear needs to be taken along; microphones, windshields,cables, mixers, headphones, etc. When the etc. starts to overwhelm you, please remember that Think Tank make a whole dedicated series of cases and bags for these new bits.
We've placed the audio-orientated products at the end of out Think Tank rack but don't think that you are restricted to just these - as you brows the TT rack you'll see that they have a case or pouch for nearly any piece of professional gear - if you work in the rain there are dedicated covers for cameras, lenses, and flashes. If you run round mountains with heavy lenses there are belt packs to evenly distribute the crushing weight that you will regret as soon as you are half-way up the slope... There are dedicated pouches for sandwiches and water bottles filled with brandy for the trip down.
Should you wish to carry your laptop through the airport there are dedicated pouches that will protect it in the overhead locker - your bigger gear can go into a rolling case with walls thick enough to stand the attention of the baggage handlers. If your arguing skills are up to it, there are deceptively small camera cases that might let you get your apparatus into the overhead locker without raising suspicion. Smile sweetly and try not to sweat.
Do I use Think Tank? Yes I do - a 17" laptop case and it is just excellent for travel.